Use of optical-spectral methods for in vivo noninvasive assessment of nanoparticles accumulation in biological tissues

Autor:	Victor B. Loschenov, Anastasiya V. Ryabova, Vladimir I. Makarov, S. Yu. Vasil’chenko
Rok vydání:	2015
Předmět:	Diffuse reflectance infrared fourier transform In vivo Chemistry Analytical chemistry Nanoparticle General Chemistry Spectral data Biomedical engineering
Zdroj:	Russian Journal of General Chemistry. 85:341-345
ISSN:	1608-3350 1070-3632
Popis:	Methods for noninvasive estimation of the nanoparticles concentration in biological tissues in vivo were developed with a view to laying the scientific groundwork for diagnosis and treatment of malignant tumors. The methods were tested in experimental animals (mice inoculated with Ehrlich carcinoma). Luminescent spectroscopy and diffuse reflectance spectroscopy were applied for examination of biotissues. A special algorithm of spectral data analysis with the use of the model solution simulating the optical properties of biotissues was devised. It was shown that the optical-spectral methods developed are effective in high-accuracy noninvasive real-time quantitative analysis of the nanoparticles accumulation in biotissues.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5b628e6fdd148ad399c0e078e59af5f2 https://doi.org/10.1134/s1070363215010491 Zobrazit plný text záznamu Plný text ve formátu PDF