Autor:	Vinod F. Patel, Richard M. Schultz, Julie N. Hardin, Gerald B. Grindey
Rok vydání:	1995
Předmět:	Stereochemistry Chemistry Organic Chemistry Clinical Biochemistry Pharmaceutical Science Prodrug Biochemistry In vitro In vivo Drug Discovery Molecular Medicine Moiety Free drug Molecular Biology Ex vivo
Zdroj:	Bioorganic & Medicinal Chemistry Letters. 5:513-518
ISSN:	0960-894X
Popis:	A series of tritylated difluorodeoxynucleosides represent novel prodrugs in which there exists a predictable correlation between the electronic nature of the aromatic substituents on the trityl moiety and the acid mediated dissociation to free drug in ex vivo, in vitro and in vivo systems.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5b5b69b4ed924b2ecac105ff18cabc06 https://doi.org/10.1016/0960-894x(95)00063-y Zobrazit plný text záznamu Full Text from ScienceDirect