Compensatory hypertrophy of one adrenal gland in rats

Autor: G. V. Kharlova
Rok vydání: 1964
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 58:1242-1245
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00785020
Popis: The left adrenal gland was removed from 200 albino rats, and a mock operation was performed on 20 animals. The adrenals were studied 24 h, 7, 10 days, 2, 5, 6 weeks, and 4 1/2 months after the operation. It was found that 24 h after the operation the weight of the right adrenal gland had increased. There was also an increase in the size of the fasciculate-reticular zone of the cortex, and in the number of mitoses in the external zona fasciculata. However, a gain in the weight of the adrenal gland was found also in the mock operation. Evidently this increase was mainly due to stress. Seven days after the operation a compensatory hypertrophy could be detected (increase in the size of the organ following excision of the contralateral gland). At these periods no hypertrophy was produced by the mock operation. One, and 4 1/2 months after the operation the weight of the adrenal was 66 to 70% of that of the 2 control adrenals.
Databáze: OpenAIRE