Use of RC-MAP in cardiac surgery
| Autor: | H. Ishikawa, E. Hasegawa, S. Konishi, M. Oki, S. Yokoyama, W. Nobuoka, K. Nakamura |
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| Rok vydání: | 1994 |
| Předmět: | |
| Zdroj: | Journal of the Japan Society of Blood Transfusion. 40:76-81 |
| ISSN: | 1883-8383 0546-1448 |
| DOI: | 10.3925/jjtc1958.40.76 |
| Popis: | Purpose:Red blood cells added MAP as a additive solution (RC-MAP), developed by the Japanese Red Cross Society, is reported to be superior to the conventional CRC in that the good quality of red blood cells can be preserved for a long term. Another advantage is that the removal of huffy coat serves to alleviate transfusion-induced adverse reactions. We used RC-MAP (preserved 10-12 days after collection) and FFP (obtained from the same donors) in a total of 10 cases requiring cardiac surgery (3 for ASD, 1 for VSD+RSV, 1 fort AVR, 1 for MVR and 4 for AC bypass) from the start of extracorporeal circulation to postoperative management. This report describes the clinical courses in these cases.Results:The mean time of extracorporeal circulation was 112.5±71.3min. The volume of bleeding from the postoperative drain ranged from 4.6 to 20ml/kg except 35ml/kg in the AVR case, showing little difference from that in the cases of blood component and fresh whole blood transfusion. Fibrinogen and prothrombin time were within the normal ranges. Free Hb and BUN returned to the normal in a short time. Renal disturbance was not found in any case. The red blood cells of RC-MAP filled in the artificial heart-lung apparatus were lableled with Cr51. The half life proved to be about 26 days with little difference from that in the cases of fresh whole blood transfusion.The time of extracorporeal circulation was longer in one of the four AC bypass cases and the AVR case than in others. The total volume of RC-MAP used throughout the course was accordingly larger in these cases. This suggested that some appropriate measures should be taken for such cases, because hypoproteinemia and relative shortage of coagulation factors might arise from MAP-induced hyperhemodilution. With this in mind, we decreased MAP content in RC-MAP immediately before use for the cases treated after the above two cases. This measure could bring a good result. |
| Databáze: | OpenAIRE |
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