One-Pot CuI/DBU-Catalyzed Carboxylative Cyclization toward Oxazolidinones Using Recyclable Molecular Sieves as Efficient Promoters for Fixation of CO2 in Water Medium

Autor:	Shu-Hui Liu, Hao-Chun Yang, Huan-Chang Lu, Chi-Wei Cheng, Kwang-Ming Lee, Chun-Ying Chen, Ting-Yu Chang, Hsiu-Hui Chen, Man-kit Leung, Syeda Zehra, Shih-Hsien Yu, Yu-Te Liu
Rok vydání:	2020
Předmět:	Carboxylation Chemistry Organic Chemistry Molecular sieve Combinatorial chemistry Catalysis
Zdroj:	The Journal of Organic Chemistry. 85:13655-13663
ISSN:	1520-6904 0022-3263
Popis:	An efficient one-pot synthesis of oxazolidinones was developed through CuI/DBU/MS joint system-catalyzed carboxylative cyclization of arylacetylene, arylaldehyde, and arylamine in water medium under a 1 atm carbon dioxide (CO2) atmosphere. The 4 A molecular sieves (MSs) were added to improve CO2 capture and facilitate carboxylation to give the products in high yields. The CuI/DBU/MS system is robust and highly effective for the reactions with different substrates, and some target products were obtained in an excellent yield of ∼96%, with no side products in the final step.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5b2f20244b0a77aed04cd50e10165728 https://doi.org/10.1021/acs.joc.0c01833 Zobrazit plný text záznamu