Matrical carcinoma with melanocytic hyperplasia mimicking nodular melanoma in an elderly Mexican male

Autor: Larisa M. Lehmer, Sebastien de Feraudy, Sama K. Carly
Rok vydání: 2019
Předmět:
Zdroj: Journal of Cutaneous Pathology. 46:442-446
ISSN: 1600-0560
0303-6987
DOI: 10.1111/cup.13445
Popis: Matrical carcinoma with melanocytic hyperplasia (MCMH), previously referred to as malignant melanocytic matricoma, is a rare variant of the uncommon pilomatrical carcinoma, occurring most often on the head/neck and upper backs of middle-aged men. Nodular lesions may resemble pigmented basal cell carcinoma or melanoma clinically. We present a case of MCMH in a Hispanic patient with history of melanoma. Histopathological clues to appropriate diagnosis include basaloid cells, numerous atypical mitotic figures, matrical differentiation, shadow cells, strong diffuse nuclear and cytoplasmic expression of s-catenin, and interspersed pigmented dendritic melanocytes.
Databáze: OpenAIRE
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