Matrical carcinoma with melanocytic hyperplasia mimicking nodular melanoma in an elderly Mexican male
Autor: | Larisa M. Lehmer, Sebastien de Feraudy, Sama K. Carly |
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Rok vydání: | 2019 |
Předmět: |
Pathology
medicine.medical_specialty Histology Pigmented basal cell carcinoma business.industry Melanoma Melanocytic hyperplasia Dermatology Atypical Mitotic Figures medicine.disease Nodular melanoma Pathology and Forensic Medicine 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Matrical Carcinoma medicine Matrical Differentiation Pilomatrical Carcinoma business |
Zdroj: | Journal of Cutaneous Pathology. 46:442-446 |
ISSN: | 1600-0560 0303-6987 |
DOI: | 10.1111/cup.13445 |
Popis: | Matrical carcinoma with melanocytic hyperplasia (MCMH), previously referred to as malignant melanocytic matricoma, is a rare variant of the uncommon pilomatrical carcinoma, occurring most often on the head/neck and upper backs of middle-aged men. Nodular lesions may resemble pigmented basal cell carcinoma or melanoma clinically. We present a case of MCMH in a Hispanic patient with history of melanoma. Histopathological clues to appropriate diagnosis include basaloid cells, numerous atypical mitotic figures, matrical differentiation, shadow cells, strong diffuse nuclear and cytoplasmic expression of s-catenin, and interspersed pigmented dendritic melanocytes. |
Databáze: | OpenAIRE |
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