Synthesis of Some Novel 2,3,4,8,9‐Pentahydro‐7‐(4‐haloaryl)‐pyrazolo[5,1‐e]benzo[1,5]oxazocines and 2,3(erythro), 7,8‐Tetrahydro‐2‐aryl‐3‐(4‐fluoro‐3‐methylbenzoyl)‐6‐(4‐haloaryl)pyrazolo[5,1‐d] Benzo[1,4]oxazepines via Solid–Liquid PTC

Autor:	Vijai N. Pathak, Ragini Gupta, Vineeta Sareen, Bindu Varshney, Ranjana Tiwari, Rekha Gupta
Rok vydání:	2007
Předmět:	chemistry.chemical_compound Oxazocines Stereochemistry Chemistry Aryl Organic Chemistry Diastereomer Regioselectivity Solid liquid
Zdroj:	Synthetic Communications. 37:977-984
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397910601163927
Popis:	In this communication, a simple and straightforward procedure for the heterocyclization of 1H‐4,5‐dihydro‐3‐(4‐haloaryl)‐5‐substituted phenylpyrazoles (4) with 1‐bromo‐3‐chloropropane and 2,3‐dibromo‐1‐(4‐fluoro‐3‐methylphenyl)‐3‐phe‐ nylpropanone affording 2,3,4,8,9‐pentahydro‐7‐(4‐haloaryl)pyrazolo[5,1‐e]benzo[1,5] oxazocines 5 and regioselective synthesis of 2,3(erythro),7,8‐tetrahydro‐2‐ aryl‐3‐(4‐fluoro‐3‐methylbenzoyl)‐6‐(4‐halophenyl)pyrazolo[5,1‐d]benzo[1,4]oxa‐ zepines 6, respectively, via solid–liquid PTC is reported. All the synthesized compounds have been characterized on the basis of their spectral studies (IR, PMR, and MS) and analytical data.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5b1cb3ba0707eedc83d99712140c7291 https://doi.org/10.1080/00397910601163927 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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