The Effect of the Combination of Demineralization Freeze Dried Dentin Matrix (DFDDM) and Moringa oleifera Lam to increase Fibroblas and Osteoblas cell in Alveolar Bone after Caviacobaya’s Tooth Extraction
| Autor: | Huldani, Irene Edith Riewpassa, Sri Oktawati, Yayah Inayah, Harun Achmad, Hasanuddin Thahir, Arni Irawaty Djais, Bayu Indra Sukmana, Dewiayu Dewang, Widodo, Nurdiana Dewi, Muchammad Hatta |
|---|---|
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Systematic Reviews in Pharmacy. 11 |
| ISSN: | 0975-8453 0976-2779 |
| Popis: | Background: The socket preservation has important role in alveolar bone resorption after tooth extraction. Various graft materials can be used in socket preservation must have osteoconductive, osteoinductive and osteoproliferation properties. Autogenous bone graft from dentin can be used because it has good osteoinductive and osteoconductive properties. One of the active substances of MoringaoleiferaLam is flavonoidsthat have several beneficial characteristics as an anti‑inflammatory. The combination of antiinflammatory with MO extract and Demineralization Freeze Dried Dentin Matrix (DFDDM) is expected to provide a good response to bone formation. Aim: To determine the potentialof combination MO and DFDDM in formation of Fibroblast and Osteoblast’s cells in post extraction caviacobaya’s tooth. Method: The mandibular incisors of 45 Caviacobaya were extracted and divided into five groups subjected to different socket preservation treatments sequentially with MO, DFDDM, combination of MO and DFDDM, Gamacha® and polyethylene glycol (PEG). The caviacobaya were examined on days 7, 14 and 21 after which the specimens were sacrificed and examined using an immunohistochemical technique. The resulting data were then analyzed using one‑way ANOVA and Tukey’s honestly significant difference tests. Result: The One Way Anova test results showed a significant difference in FIbroblast and osteoblast between the groups (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|