Cerium(IV) sulfate catalyzed one-pot three-component diastereo selective synthesis of 4-amidotetrahydropyrans
Autor: | Nagarajan Panneer Selvam, Paramasivan T. Perumal |
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Rok vydání: | 2009 |
Předmět: | |
Zdroj: | Canadian Journal of Chemistry. 87:698-705 |
ISSN: | 1480-3291 0008-4042 |
DOI: | 10.1139/v09-050 |
Popis: | A convenient and diastereoselective one-pot synthesis of cis-4-amidotetrahydropyrans is described. This simple protocol involves Prins cyclization of homoallylic alcohol and aldehydes, followed by Ritter reaction of acetonitrile leading to the formation of cis-4-acetamidopyrans in good yields. |
Databáze: | OpenAIRE |
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