Cerium(IV) sulfate catalyzed one-pot three-component diastereo selective synthesis of 4-amidotetrahydropyrans

Autor: Nagarajan Panneer Selvam, Paramasivan T. Perumal
Rok vydání: 2009
Předmět:
Zdroj: Canadian Journal of Chemistry. 87:698-705
ISSN: 1480-3291
0008-4042
DOI: 10.1139/v09-050
Popis: A convenient and diastereoselective one-pot synthesis of cis-4-amidotetrahydropyrans is described. This simple protocol involves Prins cyclization of homoallylic alcohol and aldehydes, followed by Ritter reaction of acetonitrile leading to the formation of cis-4-acetamidopyrans in good yields.
Databáze: OpenAIRE