Immune Complex Glomerulonephritis in Chronic Granulomatous Disease
| Autor: | D. J. Rhenen, M. I. Koolen, Th. M. Feltkamp‐Vroom, R. S. Weening |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry media_common.quotation_subject Renal function Disease Antimicrobial medicine.disease medicine.disease_cause Focal Glomerulonephritis Chronic granulomatous disease Staphylococcus aureus Immunology Internal Medicine medicine Girl Abscess business media_common |
| Zdroj: | Acta Medica Scandinavica. 206:233-237 |
| ISSN: | 0001-6101 |
| Popis: | An 18-year-old girl is described who developed advanced renal sclerotic lesions, probably preceded by local focal glomerulonephritis, which coexisted with a Staphylococcus aureus abscess. It is hypothesized that immune complex glomerulonephritis developed, provoked by long-term antigenic stimulation of Staphylococcus aureus. The cause of these long-term bacterial infections was a defect of the phagocytic cells to kill bacteria effectively, a disease known as chronic granulomatous disease. Therapy with intracellularly active antimicrobial agents restored the renal function till no more haemodialysis was necessary. |
| Databáze: | OpenAIRE |
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