An Efficient Preparation of Stereospecific ?-Hydroxy Nitriles

Autor:	William S. Powell, Joshua Rokach, Mustafa Adiyaman, Sheila H. Jacobo, Chih-Tsung Chang, Namin Kang
Rok vydání:	2005
Předmět:	chemistry.chemical_compound Stereospecificity chemistry Nitrile Yield (chemistry) Hydroxy group Organic chemistry General Medicine
Zdroj:	ChemInform. 36
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200514054
Popis:	The cyanide-ring opening of thionocarbonates with NaCN in DMF and TBACN in THF is described. This reaction occurred regioselectively to afford β-hydroxy nitrile with preserved stereochemistry of the hydroxy group in high yield.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5a6b4f4e4b5273f39bfe22370480f9a9 https://doi.org/10.1002/chin.200514054 Zobrazit plný text záznamu Plný text