Cepo uncovers cell identity through differential stability
| Autor: | Kevin Wang, Patrick P.L. Tam, Jean Yh Yang, Hani Jieun Kim, Yingxin Lin, Carissa Chen, Pengyi Yang, David M. Lin |
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| Rok vydání: | 2021 |
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| DOI: | 10.1101/2021.01.10.426138 |
| Popis: | We present Cepo, a method to generate cell-type-specific gene statistics of differentially stable genes from single-cell RNA-sequencing (scRNA-seq) data to define cell identity. Cepo outperforms current methods in assigning cell identity and enhances several cell identification applications such as cell-type characterisation, spatial mapping of single cells, and lineage inference of single cells. |
| Databáze: | OpenAIRE |
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