Fat mobilization in water restricted Awassi ewes supplemented with vitamin C

Autor: Elie K. Barbour, Lina S. Jaber, N. Hanna, M. Abi Said, S.K. Hamadeh, N. Rawda, Mabelle Chedid
Rok vydání: 2011
Předmět:
Zdroj: Journal of Arid Environments. 75:625-628
ISSN: 0140-1963
Popis: The current study was designed to assess the effect of water restriction on fat metabolism in Awassi ewes orally supplemented with different levels of vitamin C. Experiment 1 (24 days) included four groups, four animals in each, with one group as control receiving daily water. The three remaining groups were watered once every four days, with the third and fourth groups receiving a daily oral dose of 3 g and 5 g vitamin C, respectively. Experiment 2 (21 days) was similarly designed except that the last group was administered one 10 g vitamin C oral dose at the beginning and at the middle of the experiment. Water restriction induced a reduction in feed intake and consequently weight loss in both experiments. Fat cell diameter, insulin, leptin, T3 and T4 concentrations tended to decrease in water restricted animals with or without vitamin C, while fatty acids and cholesterol increased. The observed changes reflect fat mobilization in water restricted Awassi ewes, which seemed to be correlated with insulin and leptin levels. Furthermore, fat mobilization reflected by high fatty acid and low leptin concentrations seemed to be more enhanced by daily supplementation of vitamin C than by the singular high dosages repeated twice, however further research is needed to confirm this observation.
Databáze: OpenAIRE