Preparative gas chromatography in the industrial rubber laboratory

Autor: J. B. Pausch
Rok vydání: 1975
Předmět:
Zdroj: Chromatographia. 8:80-84
ISSN: 1612-1112
0009-5893
DOI: 10.1007/bf02284352
Popis: Preparative gas chromatography has been a practical tool to prepare laboratory quantities of highly purified materials. Actual applications have included monomer purification, separation of azeotropic mixtures, resolution of stereoisomers and solvent purification. These separations have been achieved with a modified Prepmaster using a 2.5 inch internal diameter column. Scale-up of analytical resolution to the preparative column was maintained primarily by controlling the radial gas flow distribution. Special insert baffles, were made and installed within the column. Standard liquid phases were used depending upon the separation required. A critical step in the experimental operation is the trapping of the isolated peak. Fogging was prevented by using small water-cooled columns packed with glass beads to maintain the mass transfer rate greater than the heat transfer rate. Each system required somewhat different trapping conditions. Sample sizes ranged from 2 to 25 ml and daily throughput was 10–100 ml depending upon the difficulty of the separation. Material purity greater than 99.9% was usually achieved.
Databáze: OpenAIRE
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