Silica-l-proline: An efficient and recyclable heterogeneous catalyst for the Knoevenagel condensation between aldehydes and malononitrile in liquid phase

Autor: Monika Gupta, Rupali Vaid
Rok vydání: 2014
Předmět:
Zdroj: Monatshefte für Chemie - Chemical Monthly. 146:645-652
ISSN: 1434-4475
0026-9247
DOI: 10.1007/s00706-014-1331-5
Popis: A simple and convenient methodology for the synthesis of various substituted benzylidene malononitrile derivatives using amino acid functionalized silica as heterogeneous catalyst, since amino acids recently emerged as a class of broadly useful organocatalysts for carbon–carbon bond formation reactions. This method has several advantages including good isolated yields of the products and easy workup. Moreover, the catalyst also showed good activity and could be recovered and recycled with much loss of activity rendering the process more economic and fall in the domain of green chemistry.
Databáze: OpenAIRE