1,6-hexanediol diacrylate-crosslinked polystyrene: Preparation, characterization, and application in peptide synthesis
| Autor: | C. Arunan, V. N. Rajasekharan Pillai |
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| Rok vydání: | 2003 |
| Předmět: |
chemistry.chemical_classification
Materials science Polymers and Plastics Synthetic resin technology industry and agriculture General Chemistry Polymer Divinylbenzene Surfaces Coatings and Films Styrene chemistry.chemical_compound chemistry Polymerization Polymer chemistry Materials Chemistry Copolymer Suspension polymerization Polystyrene |
| Zdroj: | Journal of Applied Polymer Science. 87:1290-1296 |
| ISSN: | 1097-4628 0021-8995 |
| DOI: | 10.1002/app.11538 |
| Popis: | A copolymer of 1,6-hexanediol diacrylate (HDODA) and styrene was prepared by a suspension polymerization method. The resin was characterized by infrared and carbon-13 cross-polarization magic-angle spin ( 13 C CP-MAS) spectroscopy. The topology of the resin was examined by scanning electron microscopy (SEM). The polymer swells extensively in common solvents used for peptide synthesis. The resin exhibited chemical stability even in neat trifluoroacetic acid. The applicability of the new resin was demonstrated by synthesis of Val-Ala-Val-Ala-Ala-Gly, Gln-Val-Gly-Gln-Val-Glu-Leu-Gly, and Val-Gln-Ala-Ala-Ile-Asp-Tyr-Ile-Asn-Gly. Comparative synthetic studies showed that the new resin is superior to divinylbenzene (DVB)-based resin in the case of the synthesis of hydrophobic peptide sequences. |
| Databáze: | OpenAIRE |
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