Toxicity and antiviral activity of cinnabarin obtained fromPycnoporus sanguineus(Fr.) Murr

Autor:	R. Tramonte, Clarice Loguercio-Leite, S. G. Carobrez, Elza de Fátima Albino Smânia, C. J. S. Marques, Artur Smânia, Carlos R. Zanetti
Rok vydání:	2003
Předmět:	Pharmacology Rabies virus Biological activity Biology medicine.disease_cause biology.organism_classification Virus Microbiology Toxicity medicine Cytotoxic T cell Cytotoxicity Pycnoporus sanguineus Cytopathic effect
Zdroj:	Phytotherapy Research. 17:1069-1072
ISSN:	0951-418X
DOI:	10.1002/ptr.1304
Popis:	This work describes the cytopathic effect on cells, cytotoxic action on mice, and antiviral activity of cinnabarin. This substance had no effect on mouse neuroblastoma cells (NA cell, ATCC clone C-1300) at a concentration of 0.31 mg/ml, it was not able to cause toxic effects in mice at concentrations of 1000 mg/kg, and reduced by four times the titers of the rabies virus at concentrations of 0.31 mg/ml. Copyright © 2003 John Wiley & Sons, Ltd.
Databáze:	OpenAIRE
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