SAYP is a novel regulator of metazoan development

Autor:	Nadezhda E. Vorobyeva, Julia L. Kuzmina, V. V. Panov, Elena N. Nabirochkina, Marina R. Kopantseva, N. V. Soshnikova, J. V. Nikolenko, Sofia G. Georgieva, Yu. V. Shidlovskii
Rok vydání:	2010
Předmět:	Genetics fungi Regulator RNA polymerase II Biology Embryonic stem cell Cell biology Imaginal disc Transcriptional Coactivator biology.protein Transcription factor II D Signal transduction Blastoderm
Zdroj:	Russian Journal of Genetics. 46:917-923
ISSN:	1608-3369 1022-7954
DOI:	10.1134/s1022795410080028
Popis:	SAYP is a dual-function transcriptional coactivator of RNA polymerase II. It is a metazoan-specific factor involved in different signaling pathways that control normal development. In Drosophila, SAYP is present in the organism from the early stages of development and participates in cell cycle synchronization at the blastoderm stage. SAYP is abundant in many embryonic cells and in imaginal discs of larvae and is crucial for oogenesis in adults. At the molecular level, SAYP serves as a basis for assembling the BTFly nuclear supercomplex consising of the Brahma and TFIID coactivators. We suppose that BTFly and other similar nuclear supercomplexes play an important role in ontogenesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5a190c6d6101eb43e3a6c32d0597e97b https://doi.org/10.1134/s1022795410080028 Zobrazit plný text záznamu Full text from SpringerLink