Structure prediction algorithm for protein complexes based on gene ontology

Autor:	Ilya A. Vakser, Alexander V. Tuzikov, Ivan Anishchenko, A. Yu. Hadarovich, Petras J. Kundrotas
Rok vydání:	2020
Předmět:	0303 health sciences 03 medical and health sciences Docking (dog) Template Gene ontology Computer science 030302 biochemistry & molecular biology Computational biology Measure (mathematics) Functional similarity 030304 developmental biology Protein–protein interaction
Zdroj:	Doklady of the National Academy of Sciences of Belarus. 64:150-158
ISSN:	2524-2431 1561-8323
Popis:	We propose an algorithm for comparing protein-protein complexes based on their functional properties in terms of Gene Ontology. The proposed measure of a functional similarity between complexes is combined with a structural measure to find templates for the template-based docking of protein complexes. We present the results on the modeling of protein complexes based on this algorithm.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5a0a7a9f8db87fbec63919c9a3095764 https://doi.org/10.29235/1561-8323-2020-64-2-150-158 Zobrazit plný text záznamu