Vitamin A, D & Zinc Serum Levels in Children with Acute Gastroentritis: A Case Control Study: Tehran, Iran
| Autor: | Shima Javadnia, Fahimeh Soheilipour, Anahita Izadi, Ali Akbar Rahbarimanesh, Samileh Noorbakhsh |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Vitamin medicine.medical_specialty Pediatrics Cross-sectional study 02 engineering and technology 03 medical and health sciences chemistry.chemical_compound Internal medicine medicine Vitamin D and neurology Elective surgery 030109 nutrition & dietetics Nutrition and Dietetics business.industry Public Health Environmental and Occupational Health Case-control study 021001 nanoscience & nanotechnology medicine.disease Diarrhea Malnutrition chemistry Etiology medicine.symptom 0210 nano-technology business Food Science |
| Zdroj: | Current Nutrition & Food Science. 12:23-27 |
| ISSN: | 1573-4013 |
| Popis: | Background and Objective: Diarrhea (as one of the main manifestations of parasitic or microbial infections in gastrointestinal tract) is still a leading cause of mortality and morbidity in children younger than 5 years old in developing countries such as Iran. Objective: Identify and compare the relationship between serum levels of zinc, vitamin A and D in children with acute gastroenteritis (AGE) and the control group to demonstrate that those who need hospitalization due to infection have lower levels of said elements. Materials and Methods: This was a cross sectional study on 25 patients with AGE in pediatric ward of Rasul Akram hospital and Bahrami Hospital during a year (2011-2012), were compared to 40 other patients who were admitted to surgical wards for elective surgery. 72% of all the patients were male and 28% were female. All patients were older than 6 months years; mean age of cases was 2.17 years. Serum levels of vitamins A and D and zinc were measured using HPLC; Radioimmunoassay; atomic methods in 2 groups. Findings: Despite the lower levels of vitamins A in cases than controls, serum levels were not significantly different (p=0.5). Serum levels of zinc were considerably but not significantly lower in cases than the controls (p=0.06). However, serum levels of vitamin D were significantly lower in AGE cases (p=0.003). Conclusion: We found lower serum levels of vitamin D in AGE cases but no difference had found in serum levels of vitamin A and zinc between the two groups probably is the end result of various effects of vitamin A and zinc on diarrhea in different age groups and AGE. This trial emphasizes therapeutic effects of vitamin D supplementation on AGE in children especially in those with malnutrition and in developing countries. Therefore, other trials on a larger scale designed to investigate discriminating different etiologies for AGE and in different age groups is performed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|