Chemical Composition Effect of Sol-Gel Derived Bioactive Glass Over Bioactivity Behavior
| Autor: | L. A. Quintero, D. M. Escobar |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Materials science
Scanning electron microscope Simulated body fluid Oxide 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Apatite 0104 chemical sciences law.invention chemistry.chemical_compound chemistry Chemical engineering law Bioactive glass visual_art visual_art.visual_art_medium 0210 nano-technology Chemical composition Layer (electronics) Sol-gel |
| Zdroj: | Proceedings of the 3rd Pan American Materials Congress ISBN: 9783319521312 |
| DOI: | 10.1007/978-3-319-52132-9_2 |
| Popis: | Bioactive glasses (BG) are a group of inorganic materials widely used in Bone Tissue Engineering (BTE). These biomaterials react with body fluids resulting in the formation of bone like apatite layer. In this study, sol-gel derived bioactive glass was synthesized in the SiO2-CaO-P2O5 system according to augmented constrained mixture experimental design, with percentage restrictions for each oxide as follows: 58 ≤ SiO2 ≤ 70; 6 ≤ P2O5 ≤ 9 and 24 ≤ CaO ≤ 34. BG were conformed into short-bulk cylinders and immersed in Simulated Body Fluid (SBF) solution for 7 and 14 days in order to carry out bioactivity tests. Apatite layer formation was confirmed by Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Analysis (EDX). The results showed apatite layer formation depended on BG chemical composition proved with p-values from ANOVA analysis below 0.05 indicating factors significance over the response. The formed apatite layer presented a Ca/P ratio similar to bone apatite, this result is appropriate for biomaterials used in BTE. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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