Bone Health Is Not Affected by Luteal Phase Abnormalities and Decreased Ovarian Progesterone Production in Female Runners1
| Autor: | B. E. Miller, Lisa C. Sequenzia, Steven A. Stier, Anthony A. Luciano, Karen M. Prestwood, Sidney Ulreich, Mary Jane De Souza, Bill L. Lasley |
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| Rok vydání: | 1997 |
| Předmět: |
Creatinine
medicine.medical_specialty Endocrinology Diabetes and Metabolism Biochemistry (medical) Clinical Biochemistry Estrone Physical exercise Urine Luteal phase Biology Biochemistry Pathophysiology Bone remodeling chemistry.chemical_compound Endocrinology chemistry Internal medicine Pregnanediol medicine |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 82:2867-2876 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem.82.9.4201 |
| Popis: | The primary purpose of this study was to determine whether decreased ovarian progesterone production, associated with short and inadequate luteal phases in exercising women, was associated with decreased bone mineral density (BMD) and altered bone metabolism. Thirty-three eumenorrheic menstruating women participated in this study for 3 months. Subjects were required to collect daily urine samples for three consecutive menstrual cycles and have blood and urine collected weekly. Daily urine samples were analyzed for free LH, estrone conjugates (E1C), and pregnanediol 3-glucuronide (PdG), adjusted for creatinine, whereas weekly blood and urine samples were analyzed for bone markers, estradiol, progesterone, FSH, and LH. Based on the analyses of these samples, subjects were divided into three groups: sedentary ovulatory (SedOvul; n = 9), exercising ovulatory (ExOvul; n = 14), and exercising luteal phase defects (ExLPD; n = 10). The three groups were matched for age (27.6 ± 1.0 yr), weight (60.6 ± 1.9 cm), and... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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