| Autor: |
A. Dupuy, Thomas Hanslik, Christophe Arena, Jean Cabane, Thierry Blanchon, Laurence Fardet, A.-S. Morin |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
British Journal of Dermatology. 163:832-837 |
| ISSN: |
0007-0963 |
| DOI: |
10.1111/j.1365-2133.2010.09877.x |
| Popis: |
Summary Background Factors influencing adherence to long-term (i.e. ≥ 3 months) systemic glucocorticoid therapy are poorly understood. Objective To evaluate the relationship between glucocorticoid-induced adverse events and therapeutic adherence in patients on long-term glucocorticoid treatment. Methods A cross-sectional survey was conducted in three departments of dermatology/internal medicine between April and September 2008. Patients were asked to provide data regarding symptoms they attributed to glucocorticoids, and adherence to treatment was measured using the four-item Morisky–Green adherence scale. Logistic regression analyses were used to assess the association between reported adverse events and adherence to glucocorticoids. Results A total of 255 questionnaires were completed and analysed [women 78%; median age 48 years (interquartile range (IQR) 34–65); connective tissue diseases 59%; median duration of treatment 24 months (IQR 8–72); median daily dose 10 mg (IQR 6–20)]. Among these 255 patients, 199 (78%) reported themselves as ‘good adherents’ and 56 (22%) as ‘poor adherents’ to treatment. Poor adherence was associated with younger age [odds ratio (OR) 0·97, 95% confidence interval (CI) 0·95–0·99, per increasing year; P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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