Tumor Secretion of Growth Factors
| Autor: | Thomas F. Deuel, William H. Daughaday |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
Cell growth business.industry Endocrinology Diabetes and Metabolism Growth factor medicine.medical_treatment Cellular differentiation Cell biology Paracrine signalling Endocrinology Epidermal growth factor Internal medicine medicine Secretion Autocrine signalling business Transforming growth factor |
| Zdroj: | Endocrinology and Metabolism Clinics of North America. 20:539-563 |
| ISSN: | 0889-8529 |
| DOI: | 10.1016/s0889-8529(18)30258-5 |
| Popis: | An increasing number of polypeptide growth factors have been identified that regulate not only cell proliferation but also an extraordinary range of cell activities, including matrix protein deposition and resolution, the maintenance of cell viability, cell differentiation, inflammation, and tissue repair. This article considers tumor secretion of insulin-like growth factor, platelet-derived growth factor, epidermal growth factor, and transforming growth factor. It also discusses their autocrine/paracrine action on tumor growth, as well as endocrine effects on other tissues. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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