Stent thrombosis associated with newer P2Y12 inhibitors (ticagrelor & pasugrel) in a STEMI patient

Autor: Ahmed Mousa, Ibrahim Mahmoud Elkhouly, Rajesh Rajan, Peter A Brady, Raja Dashti, Vladimir Kotevski, Nader Alasousi, Mohammed Al Jarallah
Rok vydání: 2019
Předmět:
Zdroj: IHJ Cardiovascular Case Reports (CVCR). 3:26-30
ISSN: 2468-600X
DOI: 10.1016/j.ihjccr.2019.04.002
Popis: A 54-year-old Kuwaiti male presented an inferior wall ST elevation myocardial infarction (STEMI). Clopidogrel 600mg was administered by the first medical contact and Ticagrelor 180 mg with intravenous (IV) glycoprotein IIb/IIIa (GP IIb/IIIa) inhibitor infusion for 24 hours after primary percutaneous intervention. Despite this, several episodes of stent thrombosis occurred during the subsequent days. Because of this, Ticagrelor was switched to Pasugrel and the patient was loaded with 60mg of Pasugrel. Unfortunately, further in-stent thrombosis occurred and therefore, after discussion, coronary artery bypass graft surgery was performed.
Databáze: OpenAIRE