Brain natriuretic peptide levels variation after left atrial appendage occlusion
| Autor: | Ana Beatriz Prieto, Jorge Palazuelos Molinero, Maria Valenzuela, Ignacio Cruz-González, Antonio Arribas Jimenez, Jorge Martín Polo, Tania Rodriguez Gabella, Ignacio Rada, Jose-Angel Perez-Rivera, Pedro L. Sánchez |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Atrial Appendage 030204 cardiovascular system & hematology Left atrial appendage occlusion 03 medical and health sciences 0302 clinical medicine Internal medicine Occlusion Intravascular volume status medicine Radiology Nuclear Medicine and imaging cardiovascular diseases 030212 general & internal medicine Contraindication Stroke business.industry General Medicine Venous blood Brain natriuretic peptide medicine.disease Anesthesia cardiovascular system Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Catheterization and Cardiovascular Interventions. 87:E39-E43 |
| ISSN: | 1522-1946 |
| DOI: | 10.1002/ccd.25985 |
| Popis: | PhDObjective: To explore the variations of brain natriuretic peptide (BNP) secretion afterleft atrial appendage occlusion. Background: Left atrial appendage occlusion hasbeen increasingly performed in the last few years, however little is known about thephysiological consequences of left atrial appendage occlusion. Left atrial appendageregulates partially intravascular volume via release of brain natriuretic peptide. Brainnatriuretic peptide levels have been related to increased risk of stroke in atrial fibrilla-tion patients. Methods: Venous blood samples were obtained in consecutive patientsundergoing left atrial appendage occlusion before, 24 hr after device implantation andat the first visit after discharge (45–60 days) for BNP measurement. Results: Left atrialappendage occlusion was performed in 34 patients with non-valvular atrial fibrillationand contraindication to long-term oral anticoagulation or at high-risk of bleeding.There were no differences in BNP levels between baseline and 24 hr after deviceimplantation. However left atrial appendage closure resulted in a significant decreasein BNP levels at the first follow-up visit (45–60 days) compared to baseline measure-ments (759.90 pg ml |
| Databáze: | OpenAIRE |
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