Changes in Left Ventricular Diastolic Function after Antihypertensive Treatment in Patients with Hypertension

Autor: Young Jin Lee, Kyu Hyung Ryu, Jong Hyung Choi, Young Bahk Koh, Dae Gyun Park, Chong Yun Rim, Kwang Seok Eom, Kyung Soon Hong, Kyoo Rok Han, Dong Jin Oh, Young Cheoul Doo, Kwang Hack Lee
Rok vydání: 1998
Předmět:
Zdroj: Journal of the Korean Society of Echocardiography. 6:61
ISSN: 1225-6021
DOI: 10.4250/jkse.1998.6.1.61
Popis: Background:Left ventricular diastolic dysfunction is often observed in hypertensive patients with normal left ventricular systolic function and can cause heart failure symptoms. Doppler echocardiography has become a standard tool for examining left ventricular diastolic function. This study was performed to evaluate the left ventricular diastolic function in hypertensive patients with normal left ventricular systolic function and to determine the changes in left ventricular diastolic function after antihypertensive treatment. Methods:Mitral inflow and pulmonary venous flow velocities were evaluated by transthoracic pulsed-wave Doppler study in patients with hypertension before antihypertensive treatment (n=50 and after antihypertensive treatment for 4 months(n=24. The patients were randomly assigned to group I to receive ACE inhibitor or group II to receive other antihypertensive drugs. Results:Before antihypertensive treatment, mitral inflow E/A ratio was 0.94±0.27, deceleration time was 222±47 msec, and pulmonary venous flow S/D ratio was 1.62±0.42. Followup Doppler study was completed in 24 patients after 4 months of antihypertensive treatment. Mitral inflow E/A ratio was significantly increased(0.96±0.24 vs. 1.16±0.25, p
Databáze: OpenAIRE