Serum BNP level expression of child patients suffering from ventricular septal defects of CHD and its relation with cardiac function and heart failure

Autor: Huixian Tao, Guojian Wang, Weidong Xu, Dan Hu
Rok vydání: 2017
Předmět:
Zdroj: Minerva Pediatrics.
ISSN: 2724-5780
DOI: 10.23736/s0026-4946.16.04786-1
Popis: BACKGROUND To explore BNP level expression of child patients suffering from ventricular septal defects of CHD and analyze the relationship between BNP and cardiac function and heart failure. METHODS To select 92 cases of child patients with ventricular septal defects of CHD in this hospital from Oct. 2012 to Sep. 2014, which were divided into no HF group (n=30), mild HF group (n=31) and moderate and severe HF group (n=31) based on the scoring standard of NYU PHFI. At meanwhile, 32 healthy children cases of the same period were taken as control group. Collect venous blood to test serum BNP level and left ventricular ejection fraction (LVEF), left ventricular ejection fraction shortening (LVFS), left ventricular end-diastolic dimension index (LVEDDI) and cardiac index (CI) of all children. RESULTS Serum BNP content and LVEDDI level of CHD child patients were obviously higher than those of the control group, while LVEF, LVFS and CI were significantly lower (P
Databáze: OpenAIRE