Quantitative Changes Occurring in the Serum Proteins During Lactation in the Ewe

Autor: B.F. Fell, E. Regoeczi, Rosa M. Campbell, W. S. Mackie
Rok vydání: 1968
Předmět:
Zdroj: Research in Veterinary Science. 9:563-575
ISSN: 0034-5288
DOI: 10.1016/s0034-5288(18)34512-0
Popis: Summary The serum of breeding ewes was analysed by the micro-Kjeldahl method for total protein and by disc electrophoresis in polyacrylamide gels. The amount of serum albumin/unit volume did not change from the end of pregnancy into the post-weaning period, but the gamma globulin fraction rose during lactation from a level that was considerably below that found in non-breeding controls to a relatively high value at weaning. The gamma globulin fraction increased at the mean rate of 0.093 g. protein/100 ml. serum/week of lactation, and there was a corresponding rise in the total protein content of the serum. A considerable increase in the number of plasma cells present in the upper gastrointestinal tract was associated with the change in composition of the serum proteins. It is suggested that the rise in serum gamma globulin that occurs during lactation is the result of an increased production that compensates, and eventually over-compensates, for a fall that appears to take place during pregnancy. The histological evidence is that the proximal parts of the small intestine may be regarded as one of the sites of the excess gamma globulin production in the lactating ewe.
Databáze: OpenAIRE