Uses of Piperonal in the Synthesis of Novel Prop-2-Enoyl Amides, Esters, Heterocyclic Systems and Study of their Antibacterial Activities
Autor: | Nadia K. El‐Aasar, Hana'a A. Al-Saman, S. A. Shiba, Ahmed K. El-Ziaty |
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Rok vydání: | 2008 |
Předmět: | |
Zdroj: | Journal of Chemical Research. 2008:500-506 |
ISSN: | 2047-6507 1747-5198 |
DOI: | 10.3184/030823408x340834 |
Popis: | Novel ( E)-3-(benzo[d][1,3]dioxol-5-yl)-2-cyanoacryloyl chloride 4 was condensed with several mono-; 1,2-; 1,3- and 1,4-bi-nucleophilic reagents containing nitrogen and oxygen to give new 2-propenoylamide and ester derivatives. Some of these amides cyclised under the reaction conditions and/or with POCl3 to give new derivatives of heterocyclic systems. Antibacterial activities were tested for nine of these products. |
Databáze: | OpenAIRE |
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