Uses of Piperonal in the Synthesis of Novel Prop-2-Enoyl Amides, Esters, Heterocyclic Systems and Study of their Antibacterial Activities

Autor: Nadia K. El‐Aasar, Hana'a A. Al-Saman, S. A. Shiba, Ahmed K. El-Ziaty
Rok vydání: 2008
Předmět:
Zdroj: Journal of Chemical Research. 2008:500-506
ISSN: 2047-6507
1747-5198
DOI: 10.3184/030823408x340834
Popis: Novel ( E)-3-(benzo[d][1,3]dioxol-5-yl)-2-cyanoacryloyl chloride 4 was condensed with several mono-; 1,2-; 1,3- and 1,4-bi-nucleophilic reagents containing nitrogen and oxygen to give new 2-propenoylamide and ester derivatives. Some of these amides cyclised under the reaction conditions and/or with POCl3 to give new derivatives of heterocyclic systems. Antibacterial activities were tested for nine of these products.
Databáze: OpenAIRE