Clerodane diterpenoids with anti-inflammatory and synergistic antibacterial activities from Tinospora crispa

Autor: Yang-Li Zhu, Li Deng, Jia-Qi Song, Yan Zhu, Rong-Wen Yuan, Xian-Zhe Fan, Hong Zhou, Ya-Si Huang, Li-Jun Zhang, Hai-Bing Liao
Rok vydání: 2022
Předmět:
Zdroj: Organic Chemistry Frontiers. 9:6945-6957
ISSN: 2052-4129
Popis: Compounds 5 and 7 exhibited nitric oxide release inhibitory activities with IC50 values of 7.5 and 10.6 μM, respectively, and compounds 9 and 14 at the sub-MIC level significantly decreased the MIC of oxacillin against MRSA from 32.0 to 1.0 and 0.5 μg mL−1, respectively.
Databáze: OpenAIRE