General synthesis of pyrido[1,2-a]indoles via Pd-catalyzed cyclization of o-picolylbromoarenes

Autor:	Padon Chuentragool, Ishmael Ochir, Zhou Li, Faraj Mahchi, Shadi Assaf, Vladimir Gevorgyan, Katrina Randle
Rok vydání:	2018
Předmět:	010405 organic chemistry Aryl Organic Chemistry 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry Pyridine ligand 0104 chemical sciences Catalysis Inorganic Chemistry chemistry.chemical_compound chemistry Materials Chemistry Physical and Theoretical Chemistry
Zdroj:	Journal of Organometallic Chemistry. 867:273-277
ISSN:	0022-328X
Popis:	An efficient Pd-catalyzed cyclization of o-picolylbromoarenes into pyridoindoles has been developed. This novel transformation, which proceeds through a not common for Pd catalysis L-to X-type pyridine ligand swap, provides an efficient route to aryl-, as well as to cyanopyrido[1,2-a]indoles, not easily accessible by existing cyclization methods.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::59491d5d8761cbe75f74cb006bb22aec https://doi.org/10.1016/j.jorganchem.2018.03.003 Zobrazit plný text záznamu Full Text from ScienceDirect