Early stage Health Technology Assessment of Electrochemotherapy of skin-directed therapy for skin melanoma and Basal Cell Carcinoma

Autor: Matej Reberšek, Leandro Pecchia, Damian Miklavčič, Eva Pirc, Marko Snoj, Aleš Grošelj, Gregor Sersa
Rok vydání: 2017
Předmět:
Zdroj: IFMBE Proceedings ISBN: 9789811051210
DOI: 10.1007/978-981-10-5122-7_182
Popis: One of the most successful medical application exploiting electroporation is an antitumor therapy called electrochemotherapy (ECT). Clinical use of electroporation in medicine is in full swing and in need of Health Technology Assessment (HTA) analysis. The early stage HTA would enable easier equipment purchase and increase opportunities for including ECT in the list of treatments covered by health insurance and raise the general awareness of electrochemotherapy cost in comparison to benchmark treatments. Few cost efficacy analysis have already been performed [1] but they are lacking information on Quality of Life (QoL) increase. The cost effectiveness of electrochemotherapy will be evaluated for treatment of skin melanoma and Basal Cell Carcinoma (BCC). Because cancer is a recurrent disease, we choose Markov modeling strategy. The article is composed of a detailed model description and procedures defined for future data collection. With this article we would also like to emphasize the importance of EQ_5D questioners, a standardised instrument for use as a measure of health outcome and numerical reporting of QoL increase.
Databáze: OpenAIRE