Rationale for a New Outpatient Drug Therapy Algorithm in COVID-19 Patients Based on the Principle of «Multi-hit» Approach
| Autor: | T. V. Shapovalenko, E. A. Sinitsyn, A. A. Zykova, A. O. Bogatyreva, A. V. Rvacheva, K. A. Zykov |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Microbiology (medical) medicine.medical_specialty Coronavirus disease 2019 (COVID-19) business.industry 030106 microbiology General Medicine Microbiology Clinical Practice 03 medical and health sciences 030104 developmental biology Infectious Diseases Pharmacotherapy Complex algorithm Ambulatory care medicine In patient Intensive care medicine business Coronavirus Infections |
| Zdroj: | Antibiotics and Chemotherapy. 66:49-61 |
| ISSN: | 0235-2990 |
| Popis: | The aim of the work was to justify the algorithm of outpatient drug therapy in patients with COVID-19, based on the principle of «Multi-hit» Approach. The algorithm is based on the published results of clinical studies and observations, authors’ own practical experience in the use and management of more than 4 thousand patients diagnosed with COVID-19 of varying severity during the 2020 pandemic. The article substantiates a complex algorithm for the treatment of outpatients with COVID-19, which includes etiotropic, pathogenetic, and symptomatic components of therapy with different mechanisms of action. The described approach is the 1st stage (outpatient) of a complex algorithm for managing patients with COVID-19. It has been successfully implemented in the system of outpatient care for patients with novel coronavirus infections in several leading medical institutions in Russia. The authors believe that the developed algorithm for providing outpatient drug therapy for COVID-19, based on the principle of multiple exposure, may be useful in real clinical practice of managing patients with coronavirus infection. |
| Databáze: | OpenAIRE |
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