The Reaction of Thiols and α,ω-Dithiols With Triphenylphosphine and Diisopropyl Azodicarboxylate

Autor:	I. D. Jenkins, D. Camp
Rok vydání:	1990
Předmět:	chemistry.chemical_classification Reaction mechanism Diisopropyl azodicarboxylate General Chemistry Medicinal chemistry Product distribution Catalysis chemistry.chemical_compound Monomer chemistry Biocatalysis Organic chemistry Triphenylphosphine Alkyl
Zdroj:	Australian Journal of Chemistry. 43:161
ISSN:	0004-9425
Popis:	α,ω-Dithiols in the presence of triphenylphosphine and diisopropyl azodicarboxylate are converted into a mixture of monomeric and polymeric disulfides. The product distribution is dependent on the alkyl chain length and the reaction conditions. In contrast to normal Mitsunobu reactions, disulfide bond formation is achieved with regeneration of triphenylphosphine. The mechanism of this reaction is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::593f5c44f0818d5da01c857df2e7b21e https://doi.org/10.1071/ch9900161 Zobrazit plný text záznamu