Phytochemical Analysis and Antibacterial Activity of Purple Leaf Extract [Graptophyllum pictum (L.) Griff] Against Streptococcus mutans

Autor:	Wisnu Setyari Juliastuti, Adioro Soetojo, Devi Eka Juniarti, Nabilla Dara Wungsu, Tuti Kusumaningsih
Rok vydání:	2021
Předmět:	Minimum inhibitory concentration Minimum bactericidal concentration biology Traditional medicine Phytochemical Graptophyllum pictum Chemistry Yeast extract General Medicine Antibacterial activity biology.organism_classification Streptococcus mutans Antibacterial agent
Zdroj:	Acta Medica Philippina. 55
ISSN:	2094-9278 0001-6071
Popis:	Background. Streptococcus mutans is the leading cause of dental caries. One of many medicinal plants, purple leaf [Graptophyllum pictum (L.) Griff], which contains flavonoids, alkaloids, tannins, steroids, and saponins, is a potential antibacterial agent. Objective. This study aimed to determine the antibacterial activity of purple leaf extract (Graptophyllum pictum L. Griff) against Streptococcus mutans. Methods. Streptococcus mutans were suspended in several Graptophyllum pictum (L.) Griff extract concentrations in a BHIB medium using the dilution method so that the concentration of 100%, 50%, 25%, 12.5%, 6.25%, 3.12%, 1.56%, 0.78% were obtained. Each tube was incubated for 24 hours, then subcultured in a Tryptone Yeast Extract Cystine medium in a petri dish using a spreader. Each petri dish was set for 24 hours; the growth of the colony, using CFU/mL unit, was manually calculated. The samples were then subjected to microbiological analysis. The Tukey's Honest Significant Difference test was performed to determine if the relationship between the sets of data in the treatment group is statistically significant (p
Databáze:	OpenAIRE
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