Distal resection margins in rectal cancer specimens: differences in assessment between surgeons and pathologists and the influence of neoadjuvant chemoradiation
| Autor: | Lucia Maria Kliemann, Daniel C. Damin, Claudio Tarta, Tiago Leal Ghezzi, Anderson Rech Lazzaron, Paulo de Carvalho Contu, B M Contin |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Colorectal cancer business.industry medicine.disease Palpation Resection Surgery Sphincter preservation 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis medicine Resection margin 030211 gastroenterology & hepatology Rectal resection Elective surgery business Neoadjuvant chemoradiotherapy |
| Zdroj: | Updates in Surgery. 73:1787-1793 |
| ISSN: | 2038-3312 2038-131X |
| DOI: | 10.1007/s13304-021-01102-7 |
| Popis: | To investigate the discrepancy between the distal resection margin (DRM) assessed by surgeons and pathologists, and the impact of neoadjuvant chemoradiotherapy (nCRT) on DRM. This study included 67 rectal cancer patients undergoing elective surgery. DRMs were assessed through four different techniques: in vivo subjective estimative, made by the surgeon before the rectal resection (by palpation and visual estimative); in vivo objective, measured with a ruler before the rectal transection; ex vivo objective, measured right after resection of the specimen; post-fixation objective measurement, conducted by the pathologist. The DRMs subjectively and objectively assessed by the surgeons were not significantly different (3.40 cm vs. 3.45 cm). There was a mean reduction in the length of DRMs of 35.6%, from 3.45 cm objectively measured by the surgeon to 2.20 cm measured by the pathologist. This difference was significant among patients that did not receive nCRT (3.90 cm vs. 2.30 cm, P |
| Databáze: | OpenAIRE |
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