Estimation of Uncertainty for Measuring Codeine Phosphate Tablets Formulation Using UV-Vis Spectrophotometry
Autor: | Ioana Diaconu, Ion Tanase, Andrei A. Bunaciu, Hassan Y. Aboul-Enein |
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Rok vydání: | 2010 |
Předmět: |
Chromatography
medicine.diagnostic_test Chemistry Experimental model Biochemistry (medical) Clinical Biochemistry Codeine Phosphate Biochemistry Quantitative determination Analytical Chemistry Ultraviolet visible spectroscopy Uncertainty estimation Spectrophotometry Electrochemistry medicine Measurement uncertainty Ishikawa diagram Biological system Spectroscopy |
Zdroj: | Analytical Letters. 43:1207-1216 |
ISSN: | 1532-236X 0003-2719 |
Popis: | Analytical results represent a very important part in a quality control program. Uncertainty estimation is an important step in method validation. The objective of this paper is to study the uncertainty of measurement estimation in the quantitative determination of codeine phosphate from pharmaceutical formulations using UV-VIS spectrophotometry. The uncertainty estimation was performed using the Ishikawa diagram. The estimation of uncertainty components proved to be a good way for the experimental model to obtain low contribution of uncertainty to the analytical result. |
Databáze: | OpenAIRE |
Externí odkaz: | |
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