Estimation of Uncertainty for Measuring Codeine Phosphate Tablets Formulation Using UV-Vis Spectrophotometry

Autor: Ioana Diaconu, Ion Tanase, Andrei A. Bunaciu, Hassan Y. Aboul-Enein
Rok vydání: 2010
Předmět:
Zdroj: Analytical Letters. 43:1207-1216
ISSN: 1532-236X
0003-2719
Popis: Analytical results represent a very important part in a quality control program. Uncertainty estimation is an important step in method validation. The objective of this paper is to study the uncertainty of measurement estimation in the quantitative determination of codeine phosphate from pharmaceutical formulations using UV-VIS spectrophotometry. The uncertainty estimation was performed using the Ishikawa diagram. The estimation of uncertainty components proved to be a good way for the experimental model to obtain low contribution of uncertainty to the analytical result.
Databáze: OpenAIRE
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