Vascular Effects of Cinnarizine in Patients with Intermittent Claudication
| Autor: | A H M Jageneau, F Ellis, W Loots, D E Hyams |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Arterial inflow
Cinnarizine Vascular smooth muscle business.industry Venous occlusion Biochemistry (medical) Cell Biology General Medicine 030204 cardiovascular system & hematology Biochemistry Intermittent claudication 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Anesthesia medicine In patient medicine.symptom Increased blood flow business Pulse wave velocity medicine.drug |
| Zdroj: | Journal of International Medical Research. 3:93-100 |
| ISSN: | 1473-2300 0300-0605 |
| DOI: | 10.1177/030006057500300206 |
| Popis: | An ECG-triggered venous occlusion Plethysmographic method to provide an index of arterial inflow, has been used in 10 patients with angiographic confirmed intermittent claudication. The differential quotient of the Plethysmographic arterial pulse has been used to provide an index of pulse wave velocity. The effect of cinnarizine, a drug which acts probably by inhibiting the calcium influx into vascular smooth muscle cells, was measured after three and seven days of administration. In this trial cinnarizine increased blood flow to the lower limb following exercise. |
| Databáze: | OpenAIRE |
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