Novel and Environmentally Friendly Synthesis of Pimavanserin (5-HT2A Receptor)

Autor:	V.V.N.K.V. Prasada Raju, Murthy Chavali, Rajesh Kumar Rapolu, Naveen Mulakayala
Rok vydání:	2019
Předmět:	03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry 030220 oncology & carcinogenesis Pimavanserin General Chemistry Combinatorial chemistry Environmentally friendly 030217 neurology & neurosurgery
Zdroj:	Asian Journal of Chemistry. 31:723-726
ISSN:	0975-427X 0970-7077
Popis:	Eco-friendly synthesis of pimavanserin was developed from the key starting material 4-isobutoxy benzylamine in three different routes using water as solvent. These reactions provide an advantage of easy workup, good yields of products and uses water as the solvent. No column purification was required for the isolation of the product.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::58ee4530da805777f9e402d2dcbb296c https://doi.org/10.14233/ajchem.2019.21808 Zobrazit plný text záznamu