ChemInform Abstract: Positional Isomers of Thienopyrimidinones

Autor:	V. A. Kovtunenko, T. T. Kucherenko, A. V. Zadorozhny
Rok vydání:	2009
Předmět:	chemistry.chemical_compound chemistry Condensation Structural isomer General Medicine Methylation Phenacyl Medicinal chemistry
Zdroj:	ChemInform. 40
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200925149
Popis:	Condensation of o-cyanomethylbenzoic acids with esters of 2-aminothiophene-3-carboxylic and 3-amino-thiophene-2-carboxylic acids to give isomeric 2-(4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-ylmethyl)-benzoic acids and their ethyl and phenacyl esters. Methylation of esters occurs at N-3. The spectroscopic characteristics of the positional isomers are compared at the level of carboxylic acids, their esters, and methylated products.
Databáze:	OpenAIRE
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