Evaluation of hepatoprotective activity of Gynandropsis gynandra

Autor:	Ethadi Sambasiva Rao, Battu Ganga Rao, Pragada Rajeswara Rao, Talluri Mallikarjuna Rao
Rok vydání:	2013
Předmět:	chemistry.chemical_compound Antioxidant chemistry Traditional medicine Hepatoprotection Chemical constituents medicine.medical_treatment Carbon tetrachloride medicine Dose dependence Gynandropsis gynandra
Zdroj:	Journal of Pharmacy Research. 6:928-932
ISSN:	0974-6943
DOI:	10.1016/j.jopr.2013.08.026
Popis:	Aim The present study was carried out to evaluate the hepatoprotective activity of different extracts of Gynandropsis gynandra . Methods The different extracts of G. gynandra at doses 100, 200 and 400 mg/kg b.w. were tested for their hepatoprotection against carbon tetrachloride (CCl 4 ) induced liver intoxication in rats. Results The extracts of G. gynandra showed a dose dependent hepatoprotection activity. Among all the extracts, methanolic extract produced maximum hepatoprotection (71.45%) at a dose of 400 mg/kg. Conclusion The results of the present investigation indicate that all the extracts of G. gynandra possess hepatoprotective activity and this effect was may be due to the presence of various chemical constituents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::58de481d706712c512ec4d367437e877 https://doi.org/10.1016/j.jopr.2013.08.026 Zobrazit plný text záznamu