Single-cell transcriptomics of a dynamic cell behavior in murine airways

Autor:	Adam L Haber, Daniel T Montoro, Sheldon JJ Kwok, Seok-Hyun Yun, Vladimir Vinarsky
Rok vydání:	2023
Předmět:	General Immunology and Microbiology General Neuroscience General Medicine General Biochemistry Genetics and Molecular Biology
Zdroj:	eLife. 12
ISSN:	2050-084X
DOI:	10.7554/elife.76645
Popis:	Despite advances in high-dimensional cellular analysis, the molecular profiling of dynamic behaviors of cells in their native environment remains a major challenge. We present a method that allows us to couple the physiological behaviors of cells in an intact murine tissue to deep molecular profiling of individual cells. This method enabled us to establish a novel molecular signature for a striking migratory cellular behavior following injury in murine airways.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::58da5b849d4d1ee554d21d305155230a https://doi.org/10.7554/elife.76645 Zobrazit plný text záznamu