Single-cell transcriptomics of a dynamic cell behavior in murine airways

Autor: Adam L Haber, Daniel T Montoro, Sheldon JJ Kwok, Seok-Hyun Yun, Vladimir Vinarsky
Rok vydání: 2023
Předmět:
Zdroj: eLife. 12
ISSN: 2050-084X
Popis: Despite advances in high-dimensional cellular analysis, the molecular profiling of dynamic behaviors of cells in their native environment remains a major challenge. We present a method that allows us to couple the physiological behaviors of cells in an intact murine tissue to deep molecular profiling of individual cells. This method enabled us to establish a novel molecular signature for a striking migratory cellular behavior following injury in murine airways.
Databáze: OpenAIRE