Comparison of postoperative analgesia after intraarticular injection of two different doses of morphine (5 mg) and Morphine (10 mg) with 0.5% bupivacaine in arthroscopic knee surgery : Randomized, double blinded prospective study
Autor: | Geetha R Acharya, Sumedha Mehta |
---|---|
Rok vydání: | 2019 |
Předmět: | |
Zdroj: | Indian Journal of Clinical Anaesthesia. 6:570-575 |
ISSN: | 2394-4994 2394-4781 |
DOI: | 10.18231/j.ijca.2019.111 |
Popis: | Introduction and Aims: Pain relief after knee arthroscopy is preferred for early recovery and mobility. We aim to compare effectiveness and safety of different doses of morphine 5mg and 10mg combined with 0.5% bupivacaine given intra- articularly after knee arthroscopy for postoperative analgesia. Materials and Methods: This prospective, double blind study was done in 80 patients of either sex, undergoing elective diagnostic / therapeutic arthroscopic knee surgery under spinal anesthesia. Patients were randomly allocated to two groups. 20 ml of 0.5% Bupivacaine with 5 mg, 10 mg morphine as additive were injected intra-articularly in Group 1 and Group 2 respectively. Postoperative analgesia was assessed by Visual Analogue Scale at the 1st, 2nd, 4th, 6th, 12th, 18th and 24th after surgery. Time of the first request of rescue analgesia when VAS>4, total rescue analgesic consumption and any side effects in first 24 hour postoperatively was recorded. Results: Time of first postoperative rescue analgesic was significantly longer in Group 2 (464.88 25.00 min) compared to Group 1 (442.75 39.79 min). Post-operative VAS score was significantly lower at 6th, 8th, 12th and 24th hour in Group 2. Total dose of analgesic used in 24 hours in Group 2 was significantly lower than Group 1. Few side effects noted in both groups were comparable. Conclusion: We conclude that intraarticular dose of 10mg Morphine is better than 5mg Morphine with 20 ml of 0.5% Bupivacaine as it provides better postoperative analgesia with longer duration and minimal side effects. Keywords: Arthroscopy, Morphine, Postoperative, Analgesia, Bupivacaine, Intraarticular. |
Databáze: | OpenAIRE |
Externí odkaz: |