Evaluation of Electrochemical Surface Treatments of Ti by using Mesenchymal Stem Cells Culture

Autor:	Ana Camila Santos dos Santos, Gabriel Pieta Dias, Daniel Oberdoerfer, Nance Beyer Nardi, Flávia Helena da Silva, Luis Frederico Pinheiro Dick, Katiane Santin
Rok vydání:	2007
Předmět:	chemistry.chemical_compound Materials science chemistry Chemical engineering Anodizing Mesenchymal stem cell Oxide chemistry.chemical_element Statistical analysis Implant Calcium Electrochemistry Controlled release
Zdroj:	ECS Transactions. 3:9-16
ISSN:	1938-6737 1938-5862
DOI:	10.1149/1.2721504
Popis:	New surface modifications on pure Ti for prosthetic implants were developed and tested. The following treatments and their combinations were studied: Pitting, anodizing, and chemical deposition of Ca-phosphates. Mesenchymal stem cells were cultured on these Ti substrates to evaluate the quality of the proposed treatments. The closing of superficial oxide pores produced by plasma anodization of Ti was carried out by chemical deposition of Ca-phosphates and others compounds by immersion methods in different baths in order to promote a controlled release mechanisms of pharmaceutical compounds from the implant to the organism. The results were evaluated by the statistical analysis of the reduction of the pores density. Cells culture results indicated that the surface treatments were able to promote cellular proliferation and complete coverage of the Ti surfaces. The obtained calcium phosphate deposition was efficient in closing approximately 50% of the pores, although the deposition was not homogenous on the whole surface.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::58c8ba28807eacb894ccf50d67f1e601 https://doi.org/10.1149/1.2721504 Zobrazit plný text záznamu