Neuropathic pain in post-burn hypertrophic scars: A psychophysical and neurophysiological study
| Autor: | D. Risso, Franco Cauda, Palma Ciaramitaro, Maurizio Stella, Giuliano Faccani, Giuseppe Migliaretti, Angela Palmitessa, G. Isoardo, Dario Cocito |
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| Rok vydání: | 2012 |
| Předmět: |
Abductor pollicis brevis muscle
medicine.medical_specialty Hypesthesia Physiology business.industry education Neurological disorder medicine.disease Median nerve Surgery Cellular and Molecular Neuroscience Physiology (medical) Anesthesia Neuropathic pain Threshold of pain medicine Neuralgia Neurology (clinical) Carpal tunnel syndrome business health care economics and organizations |
| Zdroj: | Muscle & Nerve. 45:883-890 |
| ISSN: | 0148-639X |
| Popis: | Introduction: Pain complicates hypertrophic post-burn pathologic scars (PPS) Methods: To investigate the possible neuropathic origin of pain, 13 patients with painful PPS involving at least 1 hand underwent clinical examination, including the Douleur Neuropathique en 4 questions (DN4) questionnaire; median, ulnar, and radial nerve conduction studies (NCS); cold- (CDT) and heat-induced pain threshold evaluation by quantitative sensory testing; and cutaneous silent period (CSP) testing of the abductor pollicis brevis. Controls included 9 patients with non-painful PPS, 52 healthy subjects, and 28 patients with carpal tunnel syndrome (CTS). Results: All patients with painful PPS had possible neuropathic pain (DN4 score ≥4). NCS signs of CTS were similarly present in PPS subjects with or without pain. Hands with painful PPS had lower CDT and CSP duration, more frequent cold- and heat-pain hypesthesia, and more thermal allodynia than controls. Conclusions: In PPS, possible neuropathic pain is associated with psychophysical and neurophysiological abnormalities suggestive of small-fiber damage. Muscle Nerve 45: 883–890, 2012 |
| Databáze: | OpenAIRE |
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