In Vitro Metabolism of Androgens in Dog Hypothalamus, Pituitary, and Limbic System12
| Autor: | E. Castañeda, A. E. Pérez, G. Pérez-Palacios, C. Gual, F. Gomez-Perez |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty medicine.medical_treatment In vitro metabolism Cell Biology General Medicine Biology Steroid Limbic system medicine.anatomical_structure Endocrinology Reproductive Medicine chemistry Hypothalamus Oxidoreductase Internal medicine medicine Androstenedione Target organ Hormone |
| Zdroj: | Biology of Reproduction. 3:205-213 |
| ISSN: | 1529-7268 0006-3363 |
| Popis: | When testosterone-7-3H was used as substrate, the formation of 3H-labeled 1 7�l-hydroxy-5a-androstane-3-one, androstenedione, and 5a-androstane-3,17-dione were noted. These experiments demonstrate the presence of a 17�-dehydrogenase as well as a steroid A4-5a-3-keto oxidoreductase system, the latter being involved in the formation of reduced metabolites with high biological light of the mechanisms of hormonal action BIOLOGY OF REPRODUcTION 3, 205-213 (1970) 205 activity. These results are discussed in the at the target organ level. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|