Synthetic efforts towards the tricyclic framework of avenaol
| Autor: | Kai Kikuchi, Christopher S. P. McErlean |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Stereochemistry Organic Chemistry Strigolactone 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Cyclopropane chemistry.chemical_compound chemistry Strigolactone synthesis Drug Discovery Sequence (medicine) Tricyclic |
| Zdroj: | Tetrahedron Letters. 70:153003 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/j.tetlet.2021.153003 |
| Popis: | The C-1–C-12 framework of the naturally occurring strigolactone, avenaol, was generated in just 7 steps from a readily available starting material. The key reaction in the sequence was a photoredox-catalyzed functionalization of a dibromocyclopropane. Although this delivered the epimeric stereochemistry at the cyclopropane, it informs future directions in strigolactone synthesis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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