Labelling of 1-benzyl-1-(3′-dimethylaminopropoxy)-cycloheptane fumarate (active substance of the drug Halidor®) with14C isotope
Autor: | D. Banfi, L. Pallos, G. Zolyomi, J. Volford |
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Rok vydání: | 1971 |
Předmět: |
Isotope
Organic Chemistry General Medicine Biochemistry Thin-layer chromatography Analytical Chemistry chemistry.chemical_compound chemistry Labelling Drug Discovery polycyclic compounds Benzyl group Side chain Moiety Organic chemistry Radiology Nuclear Medicine and imaging Mode of action Cycloheptane Spectroscopy |
Zdroj: | Journal of Labelled Compounds. 7:62-68 |
ISSN: | 1099-1344 0022-2135 |
DOI: | 10.1002/jlcr.2590070111 |
Popis: | In order to study the pharmacological properties and mode of action of 1-benzyl-1-(3′-dimethylaminopropoxy)-cycloheptane fumarate its labelling was performed with 14C. The radioactive carbon has been introduced into the benzyl group and into the dimethylamino moiety of the dimethylaminopropoxy side chain. The chemical and radiochemical purity of the two isotopic isomers was proved by thin layer chromatography and autoradiography. |
Databáze: | OpenAIRE |
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