Chlormezanone in Anxiety : A Drug Rediscovered?

Autor:	Nathanson Je, Karl Rickels, Jorge A. Pereira-Ogan, Warren G. Case, Parish Lc, Irma Csanalosi, Mirman Mj
Rok vydání:	1974
Předmět:	Drug Antianxiety Agent medicine.drug_class business.industry Chlormezanone Sedation media_common.quotation_subject Placebo Chlordiazepoxide Psychiatry and Mental health Tranquilizer Anesthesia medicine Anxiety medicine.symptom business media_common medicine.drug
Zdroj:	American Journal of Psychiatry. 131:592-595
ISSN:	1535-7228 0002-953X
DOI:	10.1176/ajp.131.5.592
Popis:	The efficacy of chlormezanone, an infrequently prescribed minor tranquilizer, was tested in a six-week double-blind trial involving 154 anxious outpatients. The results showed that chlormezanone (800 mg./day) was significantly more effective than placebo and was equal in effectiveness to chlordiazepoxide (40 mg./day). Chlormezanone produced significantly more sedation and more side effects, but no more attrition, than chlordiazepoxide. Furtherstudies confirming these results could establish chlormezanone as a useful antianxiety agent.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::588de45f5a07330e41b205d468e09466 https://doi.org/10.1176/ajp.131.5.592 Zobrazit plný text záznamu